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Tfrc蛋白修饰

Web蛋白质翻译后修饰 (PTMs) 进一步促进了从基因组水平到蛋白质组复杂性的增加。. PTMs 是一种化学修饰，在功能蛋白质组中发挥关键作用，因为它们调节活性、定位以及与其他细 … Web16 Jun 2024 · 转铁蛋白 (血清转铁蛋白或乳铁蛋白) 通过转铁蛋白受体 (tfrc) 介导铁摄取，fth1/ftl (铁蛋白组件) 通过自噬降解可以增加铁的水平，这些都可以促进铁死亡。而 …

TFRC protein expression summary - The Human Protein Atlas

WebThe Freedoms & Rights Coalition. 45,649 likes · 414 talking about this. "We may separately have very different frustrations, but we collectively stand together as we all ag dr silverstein crystal river https://wooferseu.com

Frontiers Identification and validation of transferrin receptor ...

Web铁死亡可以通过两条主要途径启动：外源性或转运蛋白依赖途径，以及内源性或酶调节途径。. 3. 铁积累的增加、自由基的产生、脂肪酸供应和脂质过氧化是诱导铁死亡的关键。. 4. 多种氧化和抗氧化系统，与自噬和膜修复机制一起作用，塑造了铁死亡时脂质过 ... WebTFRC is a Diagnostic and Prognostic Indicator. Firstly, we use TCGA and GEO database to build ROC curve, and found the AUC = 0.856 (GSE16515) and 0.742 (TCGA and GTEx), which means the TFRC has diagnostic significance ().Then, we used GEPIA and found that the patients with high TFRC expression had poor overall survival (p = 0.036, group cutoff = … Web关于 TFRC. Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:196,049,284-196,082,090 (from NCBI) This gene has 38 transcripts (splice variants), 283 orthologues, … color hub for kids

TFRC - an overview ScienceDirect Topics

Category:TFRC Gene - GeneCards TFR1 Protein TFR1 Antibody

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Tfrc蛋白修饰

TFRC upregulation promotes ferroptosis in CVB3 infection via …

WebTFRC INFORMATION. Proteini. Full gene name according to HGNC. Transferrin receptor. Gene namei. Official gene symbol, which is typically a short form of the gene name, … Web21 Mar 2024 · TFRC (Transferrin Receptor) is a Protein Coding gene. Diseases associated with TFRC include Immunodeficiency 46 and Combined Immunodeficiency.Among its …

Tfrc蛋白修饰

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Web13 May 2024 · TFRC-mediated iron import is at the center of this novel feed-forward loop to facilitate colonic epithelial cell survival. Mechanistically, disruption of TFRC led to a … Web9 Aug 2024 · To identify novel regulators of erythropoiesis, we performed independent forward genetic screens using the chemical mutagen ENU in mice. Among progeny displaying microcytic red-cell phenotypes, 7 independent mouse strains harboring mutations within the transferrin receptor gene Tfrc were identified. Six of the mutants, including the …

Web22 Nov 2024 · IntroductionTransferrin receptor protein 1 (TFRC), an ananda molecule associated with ferroptosis, has been identified as affecting a wide spectrum of … Web24 Nov 2011 · The Tfrc protein/mRNA was oppositely iron-regulated in Hepa 1-6 cells (groups e and f), down-regulated in BMDM cells lacking both IRPs (group g), and positively IRP immunopurified (group d; Figure 6B). As such, it is the only protein/mRNA that displays this complete regulatory response. Forty-five additional proteins meet 2 of the 4 criteria ...

Web5 Aug 2024 · 3.4 TFRC突变引起的先天性免疫缺陷 TfR1是哺乳动物发育必不可少的，Tfrc敲除小鼠显示胎死。然而，近期，发现了两个含有TFRC错义突变（Y20H）的家族。 然而， … Web大肠杆菌中重组表达. 溶解建议. 提供的重组人转铁蛋白受体产品形式为无菌过滤的澄清溶液. 保存建议. 对于重组人转铁蛋白受体产品，如果整瓶产品在2-4周内会用完，可保存 …

Web6 Apr 2024 · 转铁蛋白受体的结构及功能.doc.doc. 要】人体细胞的正常代谢需要铁，其中转铁蛋白受体（TfR）参与铁的吸收和调节。. TfR在所有细胞都呈低表达，在增殖活跃的细胞高表达。. 与正常组织相比，肿瘤组织TfR的表达显著增高，因此，TfR成为肿瘤靶向治疗的研究热 …

Web11 Jul 2024 · TFRC expression was activated by the transcription factor Sp1, which bound to a specific site in the TFRC promoter and increased TFRC transcription. Based on these data, we hypothesize that ... colorhunt ioWeb为阐明Bnc1截短突变诱发卵母细胞铁死亡的分子机理，张丹教授团队通过染色质免疫沉淀及测序（ChIP-seq）、ChIP-qPCR和双荧光素酶报告基因实验等发现并确证BNC1的下游靶基因Nf2，明确了NF2介导Hippo-YAP-TFRC/ACSL4 通路调控卵母细胞铁死亡的作用机制，并通过靶向NF2-YAP逆转了卵母细胞铁死亡导致的卵巢功能 ... dr. silverstein orthopedicWebCD71/Transferrin Receptor Rabbit pAb (A5865) Western blot analysis of extracts of various cell lines, using CD71/Transferrin Receptor antibody (A5865) at 1:1000 dilution.Secondary … colorhunt green