Webhorse: [noun] a large solid-hoofed herbivorous ungulate mammal (Equus caballus, family … Disseminated intravascular coagulation (DIC) is the abnormal (excessive) activation of hemostasis, with subsequent generation of excess thrombin and formation of microvascular thrombi (arterioles, venules, capillaries). As coagulation factors and platelets are consumed, inhibited or cleaved, … See more Over the past decade, our understanding of DIC has evolved from recognition of a severe hemorrhagic disorder to appreciation of DIC as a disease continuum. The process is initiated by inappropriate … See more Every animal with an inciting primary disease should be considered at risk for developing DIC. Confirmation of DIC is challenging because … See more We rely on a constellation of laboratory tests to diagnose DIC and there are no diagnostic test results that are specific or unique for DIC. Observed changes in test results can be caused by other disorders or preanalytical … See more Affected animals should always be treated for their primary disease with the goal of breaking or at least limiting the DIC cycle. Supportive care aimed at alleviating metabolic/hemodynamic … See more
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